The modern structure of the Ladoga structure (LS) is the result of long-term development (2.1–1.3 Ga), including continental and marginal-oceanic rifting with the opening of the Svecofennian Ocean and subsequent convergent interaction of the newly formed oceanic crust with an Archean craton. The geological development of the structure ended with intraplate discrete magmatism (Salma batholith, Valaam sill, Khopunvaar neck) and locally (Välimäki, Iokiranta, Alattu Päkülä) with Caledonian endogenous activation. The ore-bearing capacity of the structure is underpinned by two groups of metallogenic systems (MS) which developed during the Svecofennian (2.1–1.65 Ga) and Gothian (1.65–1.2 Ga) tectonic-magmatic cycles (TMC). In total, seven MSs are distinguished, associated with the corresponding number of lithogeodynamic complexes and 15 ore-forming systems. Of these, the most promising are three MSs – active continental margin (Pt, Pd, Au, As), collisional (Pt, Pd, Au, As, W), and continental-riftogenic (Sn, Zn, In, Be, Nb). The continental-rift-related system at the Karelian Craton margin (black shales and basalts with V, Mo, Pd and Au) is the earliest Svecofennian MS. Early orogenic magmatism, accompanied by Сu-Ni-Pt-Pd-Au-Sc (Kaalamo) and Fe-Ti-V (Välimäki) mineralization, occurred in an active continental margin environment. The collisional MS consists of skarnoids with W, Pb, Zn at the margins of gneissose granite domes and low-temperature ore-bearing (Au, Ag As, Sb, Te, Bi, Pd and Pt) metasomatic rocks in shear zones (Alattu-Päkülä, Janis, Kaalamo). The ore productivity of the post-collisional MS was controlled by the emplacement of shoshonite intrusions (Elisenvaara: P, La, Ce) and leycogranites (Latvasurja: W, Pb, Zn, Be, Bi; Iokiranta: Li, Ta and Nb). The main MS of the Gothian TMC in the Lake Ladoga area is continental riftrelated, linked with an anorthosite-rapakivi granite complex, and displaying a wider ore spectrum (Sn, Zn, In, Be, Сu, Fe, Ag, Au, Pt, Ta, Nb, Li, REE, Ti, P, fluorite and graphite) (Pitkäranta). The metallogenic structural-formational unconformity system is represented by the Karku uranium deposit. The metallogenic near-fault metasomatic rock system comprises the Mramornaya Gorka uranium deposit and several occurrences with U-Pb-Zn-(±As, Au) mineralization in the Ruskeala-Salmi tectonic zone. Three MSs hold the greatest promise within the Ladoga structure – the active continental margin MS (Pt, Pd, Au, As), collisional MS (Pt, Pd, Au, As, W), and continental-riftogenic MS (Sn, Zn, In, Be, Nb).