The State Biological Sanctuary (Zakaznik) of Regional Significance Simbozersky is located at the northern foot of the Khibiny Mountains and encompasses the Kuna and the Pecha Simba lake-river systems. It was established in 2003 in an area of 39,568 hectares to preserve game and rare animal species. In 2024, a comprehensive field botanical survey of the territory, a critical analysis of the literature and an inventory of herbarium materials of the Avrorin Polar-Alpine Botanical Garden-Institute of the Kola Science Сenter RAS (KPABG) and the Komarov Botanical Institute RAS (LE) were carried out. Prior to our studies, only one red-listed species (Calypso bulbosa (L.) Oakes) was known for this territory, collected in the first half of the twentieth century. Now, the presence of 13 species included in the second edition and 12 species recommended for inclusion in the third edition of the Red Book of the Murmansk Region, as well as 6 species from the Red Data Book of the Russian Federation, has been reliably established for the reserve. The most valuable habitats for conserving rare plant species were identified.